crown

I’m just a guy
with gout

I try my best
to avoid
temptation,
but

I’m no
Angel
Now, there's DUZALLO.

Here's the thing—while avoiding certain foods is a must, diet alone may not be enough. The uric acid your body makes is the bigger cause of your gout.

DUZALLO is a once-daily pill that fights uric acid
in 2 ways.

DUZALLO helped nearly twice as many people reach their target uric acid goal vs. allopurinol alone.*

Talk to your doctor to see if DUZALLO is right for you.

DUZALLO is used to lower uric acid in adults with gout who have not achieved target uric acid levels with allopurinol alone.

Now, there's DUZALLO.

Here's the thing—while avoiding certain foods is a must, diet alone may not be enough. The uric acid your body makes is the bigger cause of your gout.

DUZALLO is a once-daily pill that fights uric acid
in 2 ways.

DUZALLO helped nearly twice as many people reach their target uric acid goal vs. allopurinol alone.*

Talk to your doctor to see if DUZALLO is right for you.

Studies used lesinurad and allopurinol taken separately.

diamonds drops
Reduces
Production
Increases
Elimination

What is DUZALLO

If you’re having a hard time hitting your uric acid goal with diet and allopurinol alone, DUZALLO may be able to help. DUZALLO is a once-daily pill that
lowers high uric acid by:
1) reducing uric acid production, and
2) helping the body eliminate uric acid.

DISCOVER DUZALLO
Talking to Your Doctor

You may be hesitant to talk with your doctor about gout and your uric acid levels. Don't be! It's important to talk to your doctor and ask if DUZALLO is right for you. The topics listed here can help you have that conversation.

LET’S DO THIS
The DUZ and Don’ts

If you and your doctor decide that DUZALLO is right for you, you’ll need to know about important things like possible side effects, along with the do’s and don’ts of treatment.

DO IT TODAY

Important Safety Information

DUZALLO can cause serious side effects, including:

Kidney Problems: Some people taking DUZALLO may have kidney problems, such as a sudden decrease in kidney function (acute kidney failure). Your healthcare provider may do blood tests to check your kidneys while you are taking DUZALLO.

Serious Skin Rash and Serious Allergic Reactions: Severe and potentially life-threatening allergic reactions and skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis, and exfoliative dermatitis, have been reported in some people taking allopurinol, one of the components of DUZALLO. Stop taking DUZALLO and get emergency medical help if you have any of the following symptoms:

  • skin rash; blistering of the skin, mouth, nose, and genitals
  • painful red or purple skin that looks burned and peels off
  • joint pain; swollen glands
  • red, painful, watery eyes; persistent itching; hives
  • fever

Do not take DUZALLO if you have severe kidney problems, have received a kidney transplant or are on dialysis, have a fast breakdown of cancer cells that can lead to high uric acid (tumor lysis syndrome), have a rare inherited condition that causes too much uric acid in the blood (Lesch-Nyhan syndrome), or had a skin rash or other allergic reaction after taking allopurinol.

Liver Problems: Liver problems can happen in people who take DUZALLO. Call your healthcare provider if you have any of the following symptoms: loss of appetite, weight loss, feeling very tired, nausea or vomiting, yellowing of your skin or the white part of your eyes, itching, dark or brown (tea-colored) urine, or pain on the upper right side of your stomach.

Heart Problems: People who take DUZALLO can have serious heart problems, including heart attack and stroke. It is not known that DUZALLO causes these problems.

Blood Problems: DUZALLO can affect your bone marrow and cause low red blood cells, white blood cells, and platelets. If your blood cell counts become very low, you can get infections or have bleeding problems. Taking DUZALLO with certain other medicines can increase your chance of having blood problems.

Drowsiness: DUZALLO can cause you to be drowsy. Do not drive, operate heavy machinery, or do other dangerous activities until you know how DUZALLO affects you.

The most common side effects of DUZALLO include headache, flu, higher levels of blood creatinine (a measure of kidney function), heartburn (acid reflux), skin rash, nausea, and diarrhea. Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all of the possible side effects of DUZALLO. For more information, ask your healthcare provider or pharmacist.

What is DUZALLO?

DUZALLO is a prescription medicine that contains 2 medicines, a URAT1 inhibitor called lesinurad and a xanthine oxidase inhibitor called allopurinol. DUZALLO is used to lower uric acid levels in the blood in people with gout, when allopurinol alone has not worked well enough.

Please see Medication Guide and full Prescribing Information, including Boxed Warning.

Ironwood Contact Center for general inquiries: 1-844-374-4793.

+

Important Safety Information

DUZALLO can cause serious side effects, including:

Kidney Problems: Some people taking DUZALLO may have kidney problems, such as a sudden decrease in kidney function (acute kidney failure). Your healthcare provider may do blood tests to check your kidneys while you are taking DUZALLO.